Publications
Chen C, Piano V, Alex A, Han SJY, Huis In ‘t Veld PJ, Roy B, Fergle D, Musacchio A, Joglekar AP. The structural flexibility of MAD1 facilitates the assembly of the Mitotic Checkpoint Complex. Nat Commun. 2023 Mar 18;14(1):1529. PMID: 36934097.
Joglekar AP, Kukreja AA. How Kinetochore Architecture Shapes the Mechanisms of Its Function. Curr Biol. 2017 Aug 21;27(16):R816-R824. PMID: 28829971.
Joglekar AP, Aravamudhan P. How the kinetochore switches off the spindle assembly checkpoint. Cell Cycle. 2016;15(1):7-8. PMID: 26651501.
Joglekar AP. A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint. Biology (Basel). 2016 Nov 19;5(4):44. PMID: 27869759.
Joglekar AP, Bloom KS, Salmon ED. Mechanisms of force generation by end-on kinetochore-microtubule attachments. Curr Opin Cell Biol. 2010 Feb;22(1):57-67. PMID: 20061128; PMCID.
Roy B, Sim J, Han SJY, Joglekar AP. Kre28-Spc105 interaction is essential for Spc105 loading at the kinetochore. Open Biol. 2022 Jan;12(1):210274. PMID: 35042402.
Roy B, Han SJY, Fontan AN, Jema S, Joglekar AP. Aurora B phosphorylates Bub1to promote spindle assembly checkpoint signaling. Curr Biol. 2022 Jan 10;32(1):237-247.e6. PMID: 34861183.
Bouck DC, Joglekar AP, Bloom KS. Design features of a mitotic spindle: balancing tension and compression at a single microtubule kinetochore interface in budding yeast. Annu Rev Genet. 2008;42:335-59. PMID: 18680435.
Jema S, Chen C, Humphrey L, Karmarkar S, Ferrari F, Joglekar AP. Signaling protein abundance modulates the strength of the spindle assembly checkpoint. Curr Biol. 2023 Oct 23;33(20):4505-4515.e4. PMID: 7738972.
Banerjee A, Chen C, Humphrey L, Tyson JJ, Joglekar AP. BubR1 recruitment to the kinetochore via Bub1 enhances spindle assembly checkpoint signaling. Mol Biol Cell. 2022 Sep 1;33(10):br16. PMID: 35767360.
Humphrey L, Felzer-Kim I, Joglekar AP. Stu2 acts as a microtubule destabilizer in metaphase budding yeast spindles. Mol Biol Cell. 2018 Feb 1;29(3):247-255. PMID: 29187578.
Kukreja AA, Kavuri S, Joglekar AP. Microtubule Attachment and Centromeric Tension Shape the Protein Architecture of the Human Kinetochore. Curr Biol. 2020 Dec 21;30(24):4869-4881.e5. PMID: 33035484.
Sadanandan B, Vaniyamparambath V, Lokesh KN, Shetty K, Joglekar AP, Ashrit P, Hemanth B. Candida albicans biofilm formation and growth optimization for functional studies using response surface methodology. J Appl Microbiol. 2022 Apr;132(4):3277-3292. PMID: 34863013.
Joglekar AP, DeLuca JG. Chromosome segregation: Ndc80 can carry the load. Curr Biol. 2009 May 26;19(10):R404-7. PMID: 19467206.
Roy B, Verma V, Sim J, Fontan A, Joglekar AP. Delineating the contribution of Spc105-bound PP1 to spindle checkpoint silencing and kinetochore microtubule attachment regulation. J Cell Biol. 2019 Dec 2;218(12):3926-3942. PMID: 31649151.
Joglekar AP, Bouck DC, Molk JN, Bloom KS, Salmon ED. Molecular architecture of a kinetochore-microtubule attachment site. Nat Cell Biol. 2006 Jun;8(6):581-5. PMID: 16715078.
Hung CW, Aoh QL, Joglekar AP, Payne GS, Duncan MC. Adaptor autoregulation promotes coordinated binding within clathrin coats. J Biol Chem. 2012 May 18;287(21):17398-17407. PMID: 22457357.
Chen C, Whitney IP, Banerjee A, Sacristan C, Sekhri P, Kern DM, Fontan A, Kops GJPL, Tyson JJ, Cheeseman IM, Joglekar AP. Ectopic Activation of the Spindle Assembly Checkpoint Signaling Cascade Reveals Its Biochemical Design. Curr Biol. 2019 Jan 7;29(1):104-119.e10. PMID: 30595520.
Joglekar AP, Sinkford JC. Impression procedure for problem mandibular complete dentures. J Am Dent Assoc. 1968 Dec;77(6):1303-7. PMID: 4879994.
Aravamudhan P, Goldfarb AA, Joglekar AP. The kinetochore encodes a mechanical switch to disrupt spindle assembly checkpoint signalling. Nat Cell Biol. 2015 Jul;17(7):868-79. PMID: 26053220.
Wan X, O’Quinn RP, Pierce HL, Joglekar AP, Gall WE, DeLuca JG, Carroll CW, Liu ST, Yen TJ, McEwen BF, Stukenberg PT, Desai A, Salmon ED. Protein architecture of the human kinetochore microtubule attachment site. Cell. 2009 May 15;137(4):672-84. PMID: 19450515.
Aravamudhan P, Felzer-Kim I, Joglekar AP. The budding yeast point centromere associates with two Cse4 molecules during mitosis. Curr Biol. 2013 May 6;23(9):770-4. PMID: 23623551.
Sadanandan B, Vijayalakshmi V, Ashrit P, Babu UV, Sharath Kumar LM, Sampath V, Shetty K, Joglekar AP, Awaknavar R. Aqueous spice extracts as alternative antimycotics to control highly drug resistant extensive biofilm forming clinical isolates of Candida albicans. PLoS One. 2023 Jun 14;18(6):e0281035. PMID: 37315001.
Joglekar AP, Liu HH, Meyhöfer E, Mourou G, Hunt AJ. Optics at critical intensity: applications to nanomorphing. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5856-61. PMID: 15071188.
Roy B, Han SJ, Fontan AN, Joglekar AP. The copy-number and varied strengths of MELT motifs in Spc105 balance the strength and responsiveness of the spindle assembly checkpoint. Elife. 2020 Jun 1;9:e55096. PMID: 32479259.
Gardner MK, Bouck DC, Paliulis LV, Meehl JB, O’Toole ET, Haase J, Soubry A, Joglekar AP, Winey M, Salmon ED, Bloom K, Odde DJ. Chromosome congression by Kinesin-5 motor-mediated disassembly of longer kinetochore microtubules. Cell. 2008 Nov 28;135(5):894-906. PMID: 19041752.
Xu D, Joglekar AP, Williams AL, Hay JC. Subunit structure of a mammalian ER/Golgi SNARE complex. J Biol Chem. 2000 Dec 15;275(50):39631-9. PMID: 11035026.
Joglekar AP, Bouck D, Finley K, Liu X, Wan Y, Berman J, He X, Salmon ED, Bloom KS. Molecular architecture of the kinetochore-microtubule attachment site is conserved between point and regional centromeres. J Cell Biol. 2008 May 19;181(4):587-94. PMID: 18474626.
Joglekar AP, Bloom K, Salmon ED. In vivo protein architecture of the eukaryotic kinetochore with nanometer scale accuracy. Curr Biol. 2009 Apr 28;19(8):694-9. PMID: 19345105.
Gardner MK, Haase J, Mythreye K, Molk JN, Anderson M, Joglekar AP, O’Toole ET, Winey M, Salmon ED, Odde DJ, Bloom K. The microtubule-based motor Kar3 and plus end-binding protein Bim1 provide structural support for the anaphase spindle. J Cell Biol. 2008 Jan 14;180(1):91-100. PMID: 18180364.
Aravamudhan P, Chen R, Roy B, Sim J, Joglekar AP. Dual mechanisms regulate the recruitment of spindle assembly checkpoint proteins to the budding yeast kinetochore. Mol Biol Cell. 2016 Nov 7;27(22):3405-3417. PMID: 27170178.
Joglekar AP, Salmon ED, Bloom KS. Counting kinetochore protein numbers in budding yeast using genetically encoded fluorescent proteins. Methods Cell Biol. 2008;85:127-51. PMID: 18155462.
Joglekar AP, Xu D, Rigotti DJ, Fairman R, Hay JC. The SNARE motif contributes to rbet1 intracellular targeting and dynamics independently of SNARE interactions. J Biol Chem. 2003 Apr 18;278(16):14121-33. PMID: 12566453.
Aravamudhan P, Felzer-Kim I, Gurunathan K, Joglekar AP. Assembling the protein architecture of the budding yeast kinetochore-microtubule attachment using FRET. Curr Biol. 2014 Jul 7;24(13):1437-46. PMID: 24930965.
Verma V, Mallik L, Hariadi RF, Sivaramakrishnan S, Skiniotis G, Joglekar AP. Using Protein Dimers to Maximize the Protein Hybridization Efficiency with Multisite DNA Origami Scaffolds. PLoS One. 2015 Sep 8;10(9):e0137125. PMID: 26348722.
Joglekar AP, Hay JC. Evidence for regulation of ER/Golgi SNARE complex formation by hsc70 chaperones. Eur J Cell Biol. 2005 Jun;84(5):529-42. PMID: 16003907.
Joglekar AP, Hunt AJ. A simple, mechanistic model for directional instability during mitotic chromosome movements. Biophys J. 2002 Jul;83(1):42-58. PMID: 12080099.
Mehta JD, Joglekar AP. Vertical jaw relations as a factor in partial dentures. J Prosthet Dent. 1969 Jun;21(6):618-25. PMID: 5254501.
Joglekar AP. Biologic approach to complete dentures. J Prosthet Dent. 1973 Oct;30(4 Pt 2):700-3. PMID: 4517898.
Joglekar AP. Physiological approach to partial denture design. J Dist Columbia Dent Soc. 1968 Jun;43(2):13-8. PMID: 5248618.